In Paris, Saint-Germain usually refers to the neighborhood around the Église de Saint-Germain-des-Prés and along the boulevard Saint-Germain in the Latin Quarter on the Left Bank of the River Seine, in the 5e and 6e arrondissements.

The long boulevard Saint-Germain extends almost from the Champ-de-Mars by the Eiffel Tower to the Pont de Sully leading to the Île Saint-Louis (map).

Saint-Germain is part of the student district in central Paris. It's also the home to a number of famous historic cafés, including Les Deux Magots and the Café de Flore.